The user approves a script's described changes once, before it runs. Every action the script then asks for is checked against that approval. A script that never asked can read, but not change.
←/→ step · Space play/pause · R replay · Home/End jumpStep 4 of 4
Skipping the approval step never skips approval. The unapproved script still runs, its reads work, and its first change is refused with APPROVAL_REQUIRED so PXI can come back with a description for the user to accept.